My thoughts, for what it's worth.
First, put any time based effects in an effects loop - preferably a parallel loop.
Second, even with your nice tube buffer, make a true bypass pedal board. It's pretty easy - or at least, the circuit is - I've been using it for other things, not a pedal board, but it is easy to make and use. Having one button access to different combinations of FX is the way to go, and you get the load off your signal, blah. blah, blah...RG Keen has a good, easy circuit
HERE. You will probably need to add a pull down resistor (10K works, but higher might also work) to the latch enable circuit. Oh, and I hate the layout of the 4049 Hex inv. Buffers (it's really hard to route the PCB without jumpers, at least for a novice like me!), I'm using a CD74HC540 oct. inv. buffer, and a SN74AC573 latch, which has a better layout, is cheaper than the 373 Keen suggests, and by having eight circuits on both the buffer and latch you save yourself a bit of bother. It's quite nice to have the layout of the buffer and latch line up so easily. I'm finding I enjoy making circuit boards - ferric chloride does things to copper that look like magic, and it is pretty easy to work with (as long as you wear gloves)!
Gabriel