
The "straight" math works only if the whole output chain is "matched" from: net Power Tube output impedance" > OT Primary Impedance > OT Secondary Impedance > Speaker Load. (Note that matched does not necessary mean equal. Voltage matching is usually 1 : 10 from source > input). If not all matched, the equation must be adjusted accordingly to derive the correct output voltage.
I think this answers the question of how the NFB R functions. It is the series resistor in a voltage divider circuit. There are more complicated NFB circuits, but this is the overall framework.
The preamp doesn't matter unless it can't drive the power amp to full power. Even so, the NFB voltage divider ratio remains the same. I think this basically sums it up for guitar amps.
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Note that we are talking impedance so voltage will vary with frequency. Usually, measuring is done at the "standard" 1000Hz. But most of the guitar fundamental frequencies are lower. Also, NFB might be used to dampen speaker resonance. This gets complicated, because speaker resonance will typically be at around 100Hz or below. Also, speakers have significantly higher electrical impedance at and near their resonant frequency. So 1000Hz performance @ nominal impedance is not applicable. Caps in the NFB loop may be used to fine tune this; but this introduces phase issues: putting some of the frequency band out of time with the rest of the frequencies. Though this is not important for guitar amps.