The bias supply is surely mis-interpreted, as others say.
The power rail 20K and 2K are probably swapped, an easy thing to do in the heat of production. 2K would be a fine screen-dropper, giving a rational 350V. The higher 20K is appropriate for just the small tubes which will draw smaller current and need cleaner power.
This is perhaps THE reason the amp was unhappy. 127V on screens is just so-so-wrong. The poor starved 7591s won't make 10 watts this way. The low screen voltage with nominal G1 voltage means the outputs idle cold. The low B+ to the driver means it can't, even when provoked, swing 7691 G1s to get even the small power the low screen voltage allows.
Swap these two parts and see if it wakes up.
The tone control seems to be the James but mis-drawn or mis-built.
The cathodyne "ought" to either have 56K in bottom or have lower output taken at top of the 3K cathode resistor which then would be 5.6K (but that might mis-bias the tube). I really do not think this 56K:50K "unbalance" matters to the ear; leave it.
> I really don't think this OT is big enough to handle 6L6's
It won't melt. It may have strong color on your bottom notes; this can be useful, or you can shave some coupling caps for a lighter tone.
Real 7591 are all gone and new-made "7591" are not stocked everywhere, may be of variable quality. I think the 7591 was used because, at the time, it was cheap; things change and I'd re-tube it.
400V into 6.6K is heavy abuse for 6V6, although some amps do it.
I would install 6L6. The heater current difference, bah. You DO need to change the bias significantly. You could run 6L6 self-bias at 24 watt/each dissipation. Personally I'd remove the 25K drawn near output cathodes; that may be enough to up the bias to -40V suitable for 6L6.