My 6550's usually fail because the getters turn white. ... They start off silver, gradually turning white; and leave a white dusty residue inside the tube.
This statement scares me a little.
I've only seen white getters when the tube has lost all vacuum, such as a broken envelope, or a pin bent so badly it cracks the glass seal. Normally, you see the getters fade at the edges and eventually disappear as they combine with the gas molecules in the tube.
Download and read Getting the Most Out of Vacuum Tubes by Robert Tomer, 1960.
Now that's a complete answer! 
People under a certain age (me included) might not realize that CBS was a manufacturer of vacuum tubes, until you get some CBS-labeled tubes. So it's worth noting that Tomer wrote the book from the standpoint of a person intimately familiar with vacuum tube manufacturing.
On the topic of gas, he points out that an absolute vacuum is/was impossible to create in tubes. But the volume of gas in a tube was so minute as to be largely a non-issue, except for the mechanisms by which gas is liberated from tube elements.
In any event, I've got 1,000+ tubes (lost count a number of years ago). I've had only 1 short-circuit in almost 20 years of playing with them (heater-to-plate short from pin 2 to pin 3 of a 6L6GC). I've only had a couple with white getters, generally due to breakage in shipping or from dropping a box holding a bunch of loose tubes.
Outside that, I've never had a tube with the heater open up, and I've never had a completely dead tube that couldn't be made to provide
some amount of function in circuit. Gain, Gm, or power output may be low compared to a new tube, but they all still do
something. So it really boils down to how you evaluate their performance, and at what point you decide to pitch them.