Answering other questions:
Tube rectifier vs. MOSFET
Big power = big power supply. And
LOTS of current. That rules out tube rectifiers for any sensible plan, pretty much dictating solid state rectifiers.
The power supply will also be complex. For 6146, 6550 or KT88's and high power, you're probably looking at a B+ of 600v+, with a screen supply roughly half that. Most often, the path taken is 2x 300v power supplies (2 high voltage windings, 2x sets of rectifiers, one supply stacked on top of the other) to give 300v and 600v outputs. 600v goes to the OT and output tube plates, while the 300v supply powers output tube screens and the preamp.
EI power tranny vs. Toroidal vs. SMPS
I'd think you wouldn't consider a switch-mode power supply (SMPS) in an amp at all; they are generally big noise problems waiting to happen, and you likely can't find them off-the-shelf in the voltages/currents/VAs you'd need for such a big amp.
Toroids are great for saving space & weight, and radiate less hum due to their construction. But it may be harder to find what you want in a single toroid power transformer, if you're going for massive power supplies to build a beast.
That pretty much leaves EI transformers, and probably a mix of several for a very high-power amp.
12AX7 vs. 12AU7
The smart moves for tube bass amplification were pretty much already figured out by Ampeg & Sunn. You'd be best copying one of their preamps/phase inverter/output stage verbatim.