> the power transformer, power supply (and rectifier type), output tube (type and circuit), and output transformer (as well as phase inverter and feedback, if present) are all sized to suit each other in the original application.
AND the audio section IS an audio amplifier super-similar to a guitar amplifier.
On a simpler rig, you grab the top of the Volume pot, put one stage of gain in front, it IS a guitar amplifier.
Iskra seems to have made a lot of lab equipment. Only a few radios. The earlier Opatija deluxe seems to be a very related model. I would assume the audio section is 95% the same.
EL84 power output, worked near 10W Pdiss so 3W-4W output.
EABC80 in front, which is a hi-Mu (70) triode plus a mess of diodes to ignore. Think of half a 12AX7, 12AT7, or 6SL7.
There is an interesting tone control between the EABC and the EL. I would try to leave all this dead-stock.
The EABC grid runs to the Volume control. There is NFB from speaker back to the bottom of the tone control. This will work. In fact I am not sure it does much. (Some of this looks like anti-Capitalist engineering, more parts is more work for Workers, and good politiks.)
There is a ton of switching ahead of the Volume control for the various radio bands. Shielded wire to top of Vol pot, break here.
You can drive this directly with a guitar, but you will need a very strong arm to get near all 3 Watts out. You can put a booster pedal in front, beat it, see how you like it. The full monty would be to clear most of the EF89 socket, rewire as triode, use that as preamp. (Treat as-if it was 12AU7.)