20:1 is 20:1 but what's the difference between 100K:5K and 820:41(Fender used 820:47)?
What is the point of negative feedback? Does It have anything to do with the speaker or output transformer's frequency responce? In otherwords what's the theory behind using it in amps?
To smooth out the signal by dampening it with a bit of opposing phase signal. This can either be done locally - as in this example:
http://www.freewebs.com/valvewizard/localfeedback.htmlor 'globally' as in a tweed bassman etc. As you have already recently realised, the global feedback mechanism in most amps takes a voltage swing from the OT secondary and feeds it back to an earlier stage in the amp where the signal is opposite phase. The resistors in the GFB loop form a voltage divider so that you can control the signal being fed back. In the case of a tweed bassman and other similar GFB loops, the leg of the voltage divider is made into a pot and used in combination with a suitable cap, to enable selective bleeding off of treble frequencies, i.e. a presence control.
The Pr:Sec turns ratio in the OT affects the voltage swing you will get for your feedback loop. (An OT with a 4k Pr and a 8R sec has a Pr:Sec turns ratio of 22.36:1, whereas an OT with a 4K Pr and a 2R sec has a turns ratio of 44.72:1, so the voltage swing on the secondary of the latter will be theoretically half as much as the voltage swing on the secondary of the former). So all other things being equal, you may want to adjust the resistor (and/or cap) value(s) in the voltage divider to ensure you are getting a GFB signal of appropriate strength to have the 'right' effect.