> I was asking about floating B+ in the amp (in practice don't connecting the B- to the chassis)
Look at the first tube of a guitar amp.
Power is fed plate-cathode.
Signal is fed grid-cathode.
Guitar plug shell (and usually guitar strings) is therefore connected to first tube cathode, and thus to B-.
There "are" other ways.
Guitar signal can be transformer-isolated. However the standard guitar pickup (wound for maximum signal to a grid) is not a good source for a transformer. We "could" wind 200-ohm pickups and use a 200:20K mikcrophone transformer. Les Paul had some guitars like that. It has never been as popular as high-Z winding right to a grid.
You could come into a JFET or chip buffer, signal transformer, then floating B supply amplifier. But how do you power the buffer? Yes, it might only be 12V. But still its PT insulation can fail and put 117V or 230V on the input jack shell.
Look at the Kent amp I posted, or some later KAY amps. The first cathode returns to B- through 100K and 0.05uFd. The idea is, if B- turns out to be 117V "live", there is less than 2mA of current possible in 100K||0.05u, and this is usually "safe". (But cheap caps can short-out.) It also reduces the maximum output of the first stage.
What we want to do is be sure that EVERYTHING we can normally touch is connected together. The outside of the electric stove and the water faucet next to it. The heating radiator in the music room and the face/case/plug of the guitar amp. Historically we have metallic water (and steam) pipes throughout the house which return to cellar and to dirt around the house to the street.