My opinion is that you will find that the more "square" a chassis is, the more design problems you are likely to run into. Is it because guitar amp chassis, whether for head or combo, are traditionally so elongated? I don't think so; it's not just "tradition".
Yes, certainly you can go look at dozens of 50's hi-fi amps and they seem square (by "square", I obviously don't mean square with sides:length = 1:1, but let's say the long way is no MORE than 130% of the short way, whereas your typical guitar amp might be 3:1 or 2.5:1) And a Dyna Mk 3 is an obvious and very noteworthy counterexample to what I am saying. I have an older Pilot SA-232 stereo quad EL84 amp that is long and thin. It wasn't necessarily a design objective to make electronic stuff small back then! A bigger amp must have weighed more and was worth more and so you could charge more for it, right?
Why is this? Because most of those amps took in a 1 volt post-preamp signal and had no tone controls that required back-and-forth wire runs to tubes. With the exception of only a few, like LEAK and McIntosh, they generally used point-to-point wiring (but again, those amps had no tone controls, implying they saw a 1 volt post-preamp input) which maybe isn't as impressive-looking and perhaps not as rugged as turret-board type construction but the leads were shorter, and that matters. Obviously, such amps weren't made to go "on the road"; they were supposed to live on a bookshelf or in a cabinet their whole lives. A guitar amp typically has to start with 1/4 volt and has to run that sized signal back and forth to tone controls. Often, there is a[n extra] gain stage to make up for the losses of RC tone controls. This is where you stand to pick up hum, and frankly, that's the nuts and bolts of it. It is not so much the post-preamp portions of the circuit: it is the tone controls and how you have to wire them and what you have to run their wires next to.
The big smelly problem with experimental, non-proven layouts, is that you may well find out you have a bad hum monster, but you only find this out after you have hacked away all that metal and mounted all your parts. It's "impossible" to go back and change it and you definitely will not want to. So this means that you're stuck investing all this metalwork into the chassis, only to find out you *might* have a problem that resists a cure with all its irritating might.
I believe anyone making suggestions here is only trying to save you that particular form of grief. That's really all there is to it, as far as I'm concerned.