Hey all! I'm new here and hoping to learn... I like tube gear and building amps, but I really love thinking over new designs. I hope you guys can help me with my weird ideas and maybe I can give back to the community with what little knowledge I have

I found this 750w residential power distribution transformer for 480v to 120v conversion. Naturally, I want to run it backwards, to make the B+ supply for a
massive tube amp. OK, sanity check's not the right phrase, obviously not sane!
But I had some questions about output stages. I'd actually have 2x240v and I was thinking of rectifying and stacking them to get about +325v and +650v DC.
My first idea was stereo with PP EL34 for each channel. This seemed perfect since EL34s die at high voltage... but research indicates screen voltage is the real culprit, and I can set screens to 325v.
But EL34s need high impedance at that voltage (8k at least). Edcor offers OPTs with those ratings, but I'd like this to work for instruments or hi-fi... and I found reports that Edcor's high-impedance models distort treble:
https://www.eevblog.com/forum/projects/calling-all-tube-heads-recommend-me-an-alternative-output-transformer/ 
The expense/difficulty of finding EL34 OPTs for that voltage brought me to KT88s. I'd dismissed these because I thought my screen tap would be too
low... EL34 datasheets are the only I've seen that give explicit examples for running screens as low as 1/2 plate voltage (800v and 400v).
But then I found talk that KT88 screens should be kept lower than people realize for better tube life. Maybe 325v is perfect.
So here's my idea:
Stereo with one pair of PP KT88s each side, 650v on plates and 325v on screens. Fixed bias, expecting 100w or more per channel.
Output transformers: one Edcor CXPP100-5k per side. This is
slightly higher impedance than datasheets recommend for 560v. That seems OK, but apparently lower screen voltage might call for higher load impedance? That's a concept I don't understand. I thought high impedance mostly served to avoid high plate dissipation, and I don't understand how it relates to screen voltage.
This amp would weigh at least 70lbs

Any ideas? I'm open to totally different plans, including wiring the transformer for a single 325v supply. However, I don't see obvious ways to use significant power at such a low voltage. I'm also open to giving up, because this is silly. But I'm having fun planning it out.