Pots, sw's, tube sockets & jacks can be chassis mounted. The holes are already there. You'll need to add screw or rivet holes for tube sockets,
The problems with relays are space & the possibility of induced noise, which boils down to a space or shielding issue.
Components on handwired terminal strips, eyelet or turret boards will take up much more space than on the existing PC boards. You need to account for that in advance.
What I would do: make cardboard cutouts of the existing PC boards. Figure how to layout rows of terminal strips, eyelets or turrets to accommodate the circuits of the amp you choose to build. Maybe use a layout program. That's a time-eating learning curve if your not already facile with that.
Then cut out permanent garolite boards; add the terminal strips, eyelets or turrets; and populate.
You can add tube reverb; or keep it SS to save space.
Caveat: the more complex you make the amp, the more likely it is to have vexing and hard to trace issues; and the less likely it is to be noise free. Relatively speaking, I think few of these conversions have been done. IOW, this might be considered a research & development project, which is inconsistent with the goal of a pleasant & timely birthday gift. It just might not work right the first try. That's nobody's fault, but something to keep in mind.
EDIT: This gives me the idea to build a Blues Jr. into it (preamp section). Doug already has a board & layout for that. If issues arise it will be easier to get help.