Had a weird failure on a new build today, trying to sort out the cause.
I recently assembled the Plexi SE PCB from gapcb.com
Got everything mounted, did initial testing without tubes and voltages looked pretty good.
Installed tubes this AM, heaters lit up, no red plating, so I threw caution to the wind and decided to plug in. Ended up playing for 5-10 minutes, and it sounded great. Turned it off, grabbed the multimeter, turned it back on, and started getting weird readings. Heater voltage is still right, and voltage at the standby switch is 405V (identical to what it had been unloaded). That same 405 V is present up to the upstream side of the 270R 5W power resistor. The opposite side of the power resistor has negligible voltage (something like 90 mV). Turned off the amp, measured the resistor without de-soldering and it reads open. I'm left assuming that this 5W resistor just died on me.
As you can see from pics, no evidence of discoloration or other burned components that I see. It's easy enough to order another resistor from Mouser, but I want to make sure I dig out any hidden culprits before I just replace the victim and drive on. So... what typically causes the demise of a 5W power resistor? Any common culprits I should be looking for?

I haven't built that many of these, so this is a new one for me.