First, I want to thank everyone who put in their $0.02 cents worth – actually it was all much more valuable than that, because I wouldn't have found the problem without everyone's help. But as a result, I now have a greater breadth and depth of knowledge about building and trouble-shooting amps, so again thanks. Also, I want to apologize for not responding to everyone's posts/suggestions sooner. It's been a crazy week at work (I'm a teacher, and it's the end of the school year), and so didn't get a chance to try anything until today, and I've been working on it for the last couple of hours, going through everyone's suggestions. The result is . . .
PROBLEM SOLVED!!!!

From the suggestions on the Telecaster Guitar Forum, I again measured voltages, resistance, and continuity at all the point suggested, I couldn't find anything wrong. I measured resistances like Nickfl, Preacher and philosofriend suggested, and everything measured really good – within the ranges they mentioned. As philo also suggested, I again checked speaker response with nothing plugged in, and the slight speaker-hiss went up and down when the volume knobs were turned up and down. I also removed V1 and measured the resistance between the inside of the pin sockets of p3 & p8, and got 0.2 ohms. All still good, and thanks to corliss1, I now have my own home-brewed signal tracer.
From the Les Paul Forum, as suggested – thanks Case24, Wrench66, and Pappy58 – I double checked the heater connections and turned out the lights to make sure V1 was heating up properly. Tubes looked good, and both triodes were glowing nicely. I checked continuity of the center conductor of the shielded cable, and continuity through pin 2 of V1's tube socket. It was also suggested to check if the normal channel's shielded wire center connector was shorting to ground. I did, and it checked fine. So for everything is checking properly . . . CRAP!!!! . . . (not what I really said).
On The Gear Page Forum and the Hoffman Amplifiers Forum – thanks HotBluePlates, oldhousescott, Rockinrob86, zenas, VaughnC, Winnie Thomas, 66 Kicks, sluckey, and PRR for your input – I tried the suggestions of measuring voltage with the guitar plugged it at the normal channel plate – voltage was fine. Triple-checked the input wiring, and again everything looks good. Checked the pots again – everything checked out, and amp sound/hiss through the speaker went up and as it should with the volume pots turned up and down. Also, I checked all grounding wires and looked for cross-contact, and again everything looked and tested just fine. Unfortunately, I don't have a signal generator or oscilloscope to do the other tests; and I didn't get to the suggestion of using a second amp (suggested by a couple of posters in other forums as well).
I was going to try sluckey's suggestion of swapping the normal and bright inputs on V1, and I remembered the comment from "The Ballzz" on the Les Paul Forum, " Why the shielded cable? I agree it's the most probable cause, and not needed at all. I've built a half dozen tweed kits and never used it." This was my first build with shielded cable, so I decided to remove it from the normal channel and replace it with plain old cloth push-back wire when I did the V1 swap between normal and bright. Just before I pulled it out, I tested the center conductor to ground one more time before removing it, and voilà – the center conductor was grounding out!!! I pulled out the shielded cable, and I found a single tiny strand of cable wire with a little solder at the bottom of Pin 2. It was going over towards Pin 1, and I didn't see it because the shielded cable was blocking it!!! Apparently, every time I took measurements with V1 out, there was no grounding. But when I plugged the tube in, the sockets would move and the little strand would make contact between Pin 3 and Pin 1, grounding it out.
Long story short (too late for that I guess), I cleaned off all the solder and wire strands from Pin 2's solder connector, soldered in the non-shielded wire between V1 and the normal channel jacks, and the problem was solved. Along the way I learned a few new things, got a new piece of test equipment for my bench – you can never have too many tools (unless you ask my wife) – and best of all, I have an awesome tone machine with the 5E3. It sounds amazing, and will now be played and played until my wife complains, at which time I'll turn it down and keep playing . . . now for my next amp, I'm going to build a British-style 18 watt 1 x 12 with . . .
Again THANKS TO ALL!!!