The more power you can squeeze out of the tube, the more 'economical' your investment. YMMV
As pdf64 says, the goal of biasing for Class A operation is to achieve centre-bias, because that is where harmonic distortion and signal clipping are minimised. You get optimum signal output for a given amount of signal input (at a given plate voltage, screen voltage and load). Remember than in Class A operation, tube current is always 'on'. There's either more current or less current in the tube, but never no current. Therefore you want the bias to be optimal to achieve (as close as you can get to) an even voltage swing and maximum gain, with the maximum amount of tube current you can get away with. This may mean keeping the screen about 30 to 50V lower than the plate - depending on your reflected load (Too-high-a-load tends to make the screen over-dissipate under heavy signal conditions). If you are limited by a load that is on the high side, then you can either lower the screen voltage, or cool the bias off, to deprive the tube of power.
Class AB is different, because each opposite tube is alternately off for part of the signal cycle, and this changes the reflected load through the OT, resulting in the B load line (for that part of the cycle). (Whereas the A load line requires both tubes to be conducting at the same time). To get a tube to stop conducting, the signal swing at the grid has to be sufficiently largely negative so as to prevent plate current. This means that you need to drive the grid hard with a clean signal from the PI (to get a high negative grid voltage). But in the B load line condition, the screen is still conducting, so it gets zapped with even more current (when the plate current is off). So while you want the screen voltage to be high (to maximise gm and gain), you also don't want the bias to be so hot that the screen melts when the B load line condition starts to kick in
Meanwhile the 'on' tube wants to see a clean positive signal swing at the grid, so that the (quartered) B load for that tube pulls heaps of current through the OT (and ultimately to the speaker).
So the best place to bias the tubes in Class AB is where you get maximum current, and a decent B load line for part of the cycle. This means biasing the tubes cooler than you would solely for Class A (in order to encourage cutoff to occur, and to prevent the screens melting) but not so cold that you start getting overlapping cutoff in Class B. (You want overlapping Class A, not overlapping Class B.)
That's my story and I'm sticking to it.