besides a few dB volume drop, any reason why not to? seems a minimally invasive, simple way to help power tubes survive and last long, in amps where the screens were run far past their voltage ratings and/or are held at the same voltage as the plate.
lookin at those black and silver era Champs and Princetons... in most cases, not even a bias adjustment would be needed afterwards, as i've most commonly found them idling around 18-19W on the plate if they're original, so a cooler bias would be welcome

seems the only downside is changing a power supply dropper or two, to handle the extra current and still provide the same PI/preamp voltages. one could drop the whole B+ down at one point or another, but that would usually involve adding several components, more noticeably limiting volume or headroom, or some combination of the three. and i've found that vintage 6V6's can usually handle that 420V on the plate without too much trouble, as long as the screens are run much cooler (and the bias setting isn't insane).
of course, screen stoppers, lower grid resistance, lower B+ and likely a bias adjustment would be ideal to bring em fully within their max ratings. and just switching to those fabulous JJ 6V6S's would solve a lot of those problems right off the bat. but i'm trying to address situations where the owner wants to keep the amp as original and original-sounding as possible, wants to use vintage 6V6's as part of that, and wants to crank the amp... AND wants it to be reliable.
i've tried it a few times with good results, but i'm wondering if it's a practice that might sometimes result in increased noise or phase issues depending on other factors. haven't experienced that so far, and i would think not, since the screens aren't part of the audio circuit and are fully filtered, but i wanted to get some other takes on the idea. thanks in advance ✨️