Gotcha.
The components for V1 should be shifted right (as looking at your layout) and/or the socket shifted left. you should be able to line up the components essentially with the section of the tube they go to. Look at a blackface Fender input tube for an example. The concern is having the wiring cross over itself needlessly.
For R22 (not a bad idea, by the way), you'll need to make a good mechanical connection to the wire before soldering. It would be nice to have a mechanical standoff to support the free end of that resistor, or a solder lug on the board to support that end of the resistor. If you do place a lug or eyelet on the board, you'd like the board to be fairly close to the socket, so that the resistor body is as close as possible to the grid pin itself.
In your text notes, you remark that C11 may not be used. Yes, you don't normally see it in amps where trem is injected at this point, because the cap will tend to bypass the trem signal to ground, nullifying the effect. But wait! You can still use a bypass cap, it will need to be much smaller than typical. Use a 1-2uF bypass cap. The trem signal is going to be about 10Hz or less. The resistance the cathode bypass will work against will be somewhat less than 1.5k, because the cap also sees the internal resistance of the tube and the plate load (in series) in parallel, with the cathode resistor. Call it ~1.4k. Against 1.4k, a 2uF cap is 3dB down at about 113Hz, which should keep it from rolling off the trem signal.
For the feedback wire from the speaker jack, I'd run that wire along the rear apron, tucked into the corner formed by the top and back of the chassis, then turn 90 degrees to the right to come right up to R18. For a starting point for the feedback resistor values, steal the AA764 Champ values of 2.7k for R18 and 47 ohms for R19. Tinker R18 up and down to find the setting you like. Using 47 ohms for R19 keeps its effect on tube bias insignificant.
Your component spacing for the preamp section is probably unrealistically tight, unless you're going to be using small metallized polyester caps, such as the Xicons Doug sells. If you have some parts on hand, you may want to measure and/or physically lay them out, and see how your spacing really shakes out.
Other than that, you can probably get some space savings if you rearrange the trem circuit. Look at blackface Fender layouts for some ideas, but recognize they used ceramic disc caps which allowed a tighter spacing than polyester or polypropylene caps.