Well,
if you're going to use Doug's 125P1B, then according to his
transformer information, the output voltage is 640v CT, which means 320-0-320v. That implies 320v * 1.414 = 452v peak as a possible no-load voltage, even more if your wall voltage is high. I'd like to see 500v or more for a filter cap rating (or at least
I wouldn't choose to use a 450v cap). I know Fender got away with 450v caps, but my preference is conservative rating.
You can probably be more lax with nodes C and D, but that's your choice.
I can tell you that you will probably not want to take the 6V6 plate feed from node A if you have a speaker with decent bass response (i.e., something bigger than an 8" speaker). In a SE amp, the output tube plate does not get the benefit of hum cancellation at the OT, so if your speaker will reach down to 120Hz, you will want an extra stage of filtering prior to that plate feed.
According to some info I found on the net, the 125C3A is rated for 50mA. This is marginal for a choke that is also to carrying the plate current. Therefore, you may want to use the 125C1A (rated 90mA), which Doug sells at the same price. Or, you could leave your supply as-is, and build out to the "left" of node A with, say, a 100 ohm 3w resistor (or bigger in a 5w rating).
So either way, you will want 5 stages of filtering in your amp if you have a speaker with bass, or you will be asking us how to kill hum (which will only be done when you add that 5th stage of filtering). You will then take the second filter cap as your new "node A." Since you probably don't want to buy 2 chokes, a resistor is more easily added between the plate and screen node, and plan on ~1k, and move the choke earlier to carry the plate current. The reason is you'd like the series filter components that carry big current (those feeding the plate) to have as low impedance as possible above the frequency you're trying to filter out.
The chokes quoted are both 4H, so they look like ~3k to 120Hz. A 1k resistor between plate and screen will likely gain you enough filtering while not knocking down your B+ too much. It's fine for the screen to be roughly equal to the plate voltage.
The 68k grid stopper on the 6V6 seems excessive.
My gut reaction is that the preamp design is not a good idea. Specifically, I'd question the layout implied by running the signal through 1/2 a 12AX7, out to a pentode, then back through the other half of the original 12AX7. That seems like a sure recipe for oscillation, because input and output wiring will almost certainly cross over each other, with lots of gain in between. Was this a proven method from someone else's amp, or a means of chopping down a bigger design (with an extra channel or effects) into a 2-preamp tube package?
I wouldn't want to speculate on good B+ values for this circuit, given that likely problem. If you just
have to have triode-pentode-triode, I'd suggest accepting 3 preamp tube sockets and use a 7-pin (maybe 6AT6) for the cathode follower, or use a 9-pin and omit a triode. Or maybe you use that extra triode for something like trem. The input tube position could stay a 9-pin, possibly with a paralleled triode.