Read this:
http://thetubestore.com/tungsol5881.htmlPull those RI TS 5881's and use a true 6L6GC-type tube-- bias to @60% of 30 watt dissipation----the studio across the hall from my workshop has a SF Bassman 100 that i've serviced up a couple of times--- i've put in two quads of Sovtek 6L6WXT+ tubes over the last several yrs---- this amp gets massive hrs of use for both bass and guitar and it just keeps going, except for one time the heater circuit burned up from coming into contact with plate lead--- PT survived that-- i re-wired the heater circuit and it's still going strong yrs later.
I firmly believe that the problem in your amp is the use of underated output tubes--- It's a miracle that any of them have lasted this long--- the only 5881 that would hold up under those conditions is the Sovtek 5881, and it's not a true 5881 anyway--- but it is a known tough tube that will take a great deal of abuse.
Again, i suggest the Sovtek 6L6WXT+ tube for that amp----- rugged, inexpensive, and good sounding--- i use a lot of them in builds, re-tubes, etc---- It's not a glamorous tube but it is a good, honest performer.
Doug sells the EH 6L6 tube which is similar, if not identical, to the Sovtek 6L6WXT+--- buy a quad from Doug, bias them, and you're in business.
It seems that most other possibilities involving the amp failures have been ruled out---new bias circuit parts, you've checked bias voltage and checked for coupling caps leaking voltage to output tube grids.
But still the underated tubes fail----- Why ? Because they are not rated for the conditions to which they're being subjected--- they overheat and die.....................................gldtp99