Hey TIMBO, glad to see you're having some real fun down there

If it makes you feel any better,,,,,I've changed the circuit in my amp 3-4 times in the past couple months....
I'm just looking through your post and thought i'd give my 2 cents....I'm obviously no expert, but here's what I picked up on...
I would not use a 1k cathode resistor with the 220k plate OD resistor. Maybe try something like 2.2k to 3.3k with a 1uf or .68 cathode cap?
I think tubenit is hitting on a good point here....He's referring to V2b,,,,and it stood out to me as well...
The way that tube is set up, you have a ton of gain there (with 1K cath. res.), and the bypass cap value (.047uf) is boosting a range of higher freq. that could be exaggerating the perceived hiss.....combined with the same cap value on V1b and it would seem like you are trying to boost a selected range of high freq. that would probably exaggerate your hiss....(because you're making the highs, including the hiss, a lot louder than the mids and lows)

If you'd like to see a huge change (just for reference + experimentation),,,put a 4.7K (or larger value) cathode resistor on V2b and see what happens (much less gain, AND much less amplification of the hiss?),,,,while you're there, change out the V1b + V2b bypass caps for anything up to 4.7uf, so you're boosting more of the entire freq. range
Is there a possibility that i do not have enough PS filitering as i have 5 triodes hanging off one (E) node????
YES,

I think you could be picking up some hiss there,,,,and now that you've identified that the hiss is being amplified in that V1-V2 area,,,you're onto something..
Squeeze another filter cap in ther and create another node....good idea
Wait for someone to confirm or correct my thoughts,(because I have been known to say some dumb sh!+

) but sometimes it's just in the wording of things that helps me get past something

I created this cathode board in my project to be able to make cathode component value changes quicker,,,and I really appreciate having pots for cath. resistors, so I truly can dial in the gain stages, and hear and feel the results of the interaction of stages....(the 2 trim pots on the left act as variable cathode resistors for my 3rd and 4th stage)
For the record,,,how attached are you to the 2 input topology?
Keep having fun

......I am