... I am curious what can cause such a noise through the speaker cab when the amp is on, but also on standby ...
To make sure I understand, the amp is in standby so if you try to play you get no sound. Right?
Can you carefully measure voltage inside the amp and verify that the B+ to the center-tap of the output transformer is cut off when standby is engaged? Doing this tells you something important: the hum can't be coming from any of the amp circuit, because the output tubes are unable to conduct (effectively turning off all the audio path of the amp).
If that happens, there's only one way to get hum to the speakers: the power transformer radiates hum into either the speaker cabling or into the output transformer, which remains connected to the speakers.
Can you post a photo of the power and output transformers? If the core laminations of both transformers sit in the same plane (and are close enough), the power transformer can radiate hum into the output transformer. Often, the PT is a laydown type while the OT stands upright, which puts the laminations at 90-degree angles. This minimizes hum coupling. Or two upright transformers are arranged with one rotated 90-degrees.
... The only change I can think of is that I quit using my Ultimate Attenuator with the amp. ...
If you were using an attenuator, it might have been reducing the hum (along with everything else) enough for you to not notice. If you only played loudly with the attenuator removed, you might have again covered up the hum. *IF* the PT is coupling hum into the OT, it is a set level regardless of how loud you're playing. So if you play softer, you'll hear the hum more prominently. But if you use an attenuator, it's knocking down the level of everything traveling on the speaker cables, hum included.
Assuming I've guessed correctly, you see why it's important to know about everything that changed once the problem starts?