Consider 2 things:
1. If the hiss level changes when the Treble pot is rotated, then the hiss originates prior to that pot (this means it's in the 1st gain stage for that channel).
2. It's normal for hiss to increase/decrease with a Treble pot change, as much of the hiss sounds like a treble frequency.
Tubes can be noisy, but so can resistors. Quite a lot of things can contribute to overall noise floor.
However, since we are considering just the first gain stage, you might consider replacing (one at a time, so you know which had an effect) the series 68kΩ resistors from the input jacks, then 1MΩ to ground at the input jacks, the 100kΩ plate resistor, the 100kΩ slope resistor in the tone stack, and the 1.5kΩ cathode resistor. Metal film will have the least noise of readily available types in these values.
You mentioned having already replaced all 100kΩ resistors with (I presume) metal oxide resistors.
That's fine and you can move on from there. If you want to test the input jack resistors before wrestling with them, you can use a short jumper with alligator clips to ground the point where the two 68kΩ resistors are tied to the input stage grid wire. That will eliminate the 68kΩ & 1MΩ resistors from the circuit.
I'd probably do the above to see if replacing the 1.5kΩ cathode resistor seems warranted.
You'll have to decide how quiet is "quiet enough". Carbon comp resistors will be noisier than carbon film, which themselves can be noisier than metal film, which are again noisier than wirewound (where the resistance is low enough to permit use of a wirewound resistor). And older carbon comps will be hissy compared to new carbon comps. That said, lots of part-swapping can impact resale value of a vintage amp, and most old amps are noisy compared to a new build.
Only you can decide how low the noise floor must be, and when to call it "good enough". Note also there is some lower limit of noise which you simply can't reduce, which is due to thermal noise and how tubes function.