AFAIK, sleeping sickness is reversible. Run the tube with bias for an hour. True, the initial impression is "sick", but it recovers.
The history of sleeping sickness is convoluted. Early tube work never ran tubes no-current (what use is that?). Tube computers however could have digits that stayed zero for long periods. The million-dollar digit in a $100,000 budget. The day that last digit is needed, it doesn't want to take its One. This was a big deal. The initial fix mostly went to impurities in the Cathode Nickel (you need some, not others). The total tube industry's need for cathode nickel was a fly-speck in US Nickel's daily production, but it was a Critical Resource. Government, tube makers, and the nickel syndicate had already agreed that one large ton of special-brew nickel, tested by tube makers, would be THE nickel for the year. So the sleeping sickness cure covered all receiving tubes of that era.
Ah, but yes, nobody builds tube computers anymore, metallurgy and its market have changed. Perhaps new-made tubes do get sleeping sickness? Or maybe the magic mix is now so easy that you just check some boxes on the nickel order? I dunno. I do not think I have seen forum trouble-stories explainable by sleeping sickness. Of course forum tales are few and often confused. However I have seen posts about long-stored vintage tubes starting poorly and coming to full life after some hot-time.
Agree that it costs about nothing to throw a 220k-1Meg plate to B+ to keep the juice flowing.