^what sluckey and pdf64 said^
In an amplifier, any signal between the input transducer (guitar pup) and the output transducer (speaker) amounts to changes in current. From Michael Faraday, we know that changing current within any wire produces an electro-magnetic field* surrounding each wire, and if another wire is present nearby (i.e. ‘nearby’ enough to be within the same electromagnetic field surrounding the first wire), the changing current (‘signal’) in the first wire can be induced into the second wire through electromagnetic induction.
*and the higher the signal voltage (or the greater the signal current), the bigger the electromagnetic field will be.
Your layout is full of copious amounts of wires that can generate parasitic signal induction coupling between different parts of the circuit where you don’t want parasitic inductive coupling. Could be causing all sorts of feedback loops (including positive feedback resulting in oscillation). Tried and true amplifier layouts (like vintage Fender amps) were deliberately laid out in a particular way to avoid unwanted parasitic induction between different parts of the circuit. If you’re getting HF oscillation, you may want to start from scratch with your design and consider something along the lines of a more traditional vintage amp layout to avoid this. YMMV